i haven’t used gomuks, i’m not a big fan of terminal applications
nheko has so many issues. one version it was impossible to login. then when they fixed that, the encryption kept breaking and a lot of messages from my friends were lost. it also lacks a lot of features. last time i tried nheko was in january. so maybe they have fixed the stability issues and added some modern features; but otherwise it can’t compete because it can’t be used as a daily driver.
gnome currently because nearly everything i use is designed for gnome and looks mismatched on other DEs. but the gnome workflow largely feels like a prison.